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Sourav , P. and Shilpi, and Lal, G. (2015) Role of gamma-delta (gd) T cells in autoimmunity. Journal of Leukocyte Biology, 97. pp. 259-271.

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gd T cells represent a small population of overall T lymphocytes (0.5–5%) and have variable tissue distribution in the body. gd T cells can perform complex functions, such as immune surveillance, immunoregulation, and effector function, without undergoing clonal expansion. Heterogeneous distribution and anatomic localization of gd T cells in the normal and inflamed tissues play an important role in alloimmunity, autoimmunity, or immunity. The cross-talk between gd T cells and other immune cells and phenotypic and functional plasticity of gd T cells have been given recent attention in the field of immunology. In this review, we discussed the cellular and molecular interaction of gd T cells with other immune cells and its mechanism in the pathogenesis of various autoimmune diseases.

Item Type: Article
Additional Information: This is Open Access Journal (for full text click obove weblink)
Subjects: Infection and Immunity
Depositing User: Mr. Rameshwar Nema
Date Deposited: 29 Apr 2015 05:54
Last Modified: 18 Dec 2021 13:56
URI: http://nccs.sciencecentral.in/id/eprint/165

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