More , T. and Choudhury, R.S. and Gollapally, K. and Patel, S.K. and Gowda, H. and Chaudhury, K. and Rapole, S. (2016) Metabolomics and its integration with systems biology: PSI 2014 conference panel discussion report ☆. Journal of Proteomics, 127 (Part A). pp. 73-39. ISSN Volume 127, Part A, 8 September 2015, Pages 73–79

Text 53.Dr. Rapole (J. Proteomics) author copy.pdf Restricted to Registered users only Download (1247Kb) | Request a copy

Abstract

Metabolomics, being a relatively new field, is facing multiple challenges related to data acquisition and interpretation, reproducibility across analytical platforms, integration with other omics approaches and translation into theragnostic biomarkers. There is an immediate need to overcome these challenges in order to make metabolomics more useful and reliable in terms of improving our current understanding of disease biology and help in developing predictive biomarkers. Researchers interested in metabolomics gathered for a panel discussion on ‘Metabolomics and its integration with systems biology’ during the 6th Annual Meeting of Proteomics Society-India and International Conference on “Proteomics from Discovery to Function” held at the Indian Institute of Technology, Bombay from December 7–9, 2014. The panel discussed various challenges related to metabolomics and also proposed several effective solutions for optimum implementation of metabolomics in clinical practice. The key areas of panel discussion were improvement in metabolite databases with comprehensive spectral libraries, need for extensive bioinformatics tools for integrative approaches and serious considerations for clinical validation of the biomarkers for the successful implementation of metabolomics in clinics.

Item Type:	Article
Subjects:	Bioinformatics and Proteomics
Depositing User:	Mr. Rameshwar Nema
Date Deposited:	15 Dec 2016 01:58
Last Modified:	25 Feb 2021 11:39
URI:	http://nccs.sciencecentral.in/id/eprint/325

Actions (login required)

View Item