Panda , A. and Islam , S. and Santra , M.K. and Pal , S. (2015) Lead tetraacetate mediated one pot oxidative cleavage and acetylation reaction: an approach to apio and homologated apio pyrimidine nucleosides and their anticancer activity. RSC Adv., 2015,5, 82450-82459 , 5. pp. 82450-82459.

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Abstract

An efficient and versatile strategy of general applicability towards apio and homologated apio pyrimidines has been delineated. The methodology shows tosylation followed by in situ cyclization and one pot oxidative cleavage and acetylation by Pb(OAc)4 as the key steps. The methodology has been applied to D-ribose and D-mannose derivatives to achieve asymmetric synthesis of apio and homologated apio pyrimidine nucleosides.

Item Type:	Article
Subjects:	Cancer Biology
Depositing User:	Mr. Rameshwar Nema
Date Deposited:	15 Dec 2016 03:06
Last Modified:	15 Dec 2016 03:06
URI:	http://nccs.sciencecentral.in/id/eprint/329

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