Kulkarni , N. and Lal G., G. (2017) Chemokines, an answer to the gut inflammation? Atlas of Science.

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Abstract

Our gut is a complex organ which not only digests the food but also acts as an immune organ. The gut is lined by a single layer of specialized cells called as intestinal epithelial cells (IECs) which form a physical barrier between the gut and an external environment which contains a variety of foreign materials like food and gut microorganisms. IECs are underlined by specialized immune tissue called as gut-associated lymphoid tissue (GALT) which contains different kinds of ‘ready to attack’ immune cells like T cells, B cells, dendritic cells, and macrophages. IECs form a strong sensing device that responds to the external stimuli by secreting specific messenger molecules called as cytokines and chemokines which play a major role in shaping the local immune system and maintaining gut in a healthy state.

Item Type:	Article
Subjects:	Infection and Immunity
Depositing User:	Mr. Rameshwar Nema
Date Deposited:	13 Dec 2018 11:07
Last Modified:	16 Feb 2021 05:06
URI:	http://nccs.sciencecentral.in/id/eprint/541

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