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Paul, S. and Chhatar, S. and Mishra, A. and Lal, G. (2019) Natural killer T cell activation increasesiNOS(+)CD206(-) M1 macrophage and controls the growth of solid tumor. Journal for ImmunoTherapy of Cancer, 7 (1). p. 208.

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NKT cells play an important role in anti-tumor immunity. Alpha-galactosylceramide (α-GalCer), a synthetic glycolipid is presented to natural killer T (NKT) cells by most antigen-presenting cells through CD1d molecules leading to activation of NKT cells. However, the precise mechanisms of how α-GalCer-activated NKT regulate the polarization of the macrophages and effector T cells in the solid tumor are not studied adequately.

Item Type: Article
Depositing User: Mr. Rameshwar Nema
Date Deposited: 21 Feb 2020 09:04
Last Modified: 21 Feb 2020 09:04
URI: http://nccs.sciencecentral.in/id/eprint/744

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