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Guhe, V. and Soni, B. and Ingale, P. and Sing, S. (2020) Autophagy proteins and its homeostasis in cellular environment. In: Advances in Protein Chemistry and Structural Biology. Elsevier.

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Autophagy is a lysosome-dependent cellular degradation program that responds to a variety of environmental and cellular stresses. It is an evolutionarily well-conserved and essential pathway to maintain cellular homeostasis, therefore, dysfunction of autophagy is closely associated with a wide spectrum of human pathophysiological conditions including cancers and neurodegenerative diseases. The discovery and characterization of the kingdom of autophagy proteins have uncovered the molecular basis of the autophagy process. In addition, recent advances on the various post-translational modifications of autophagy proteins have shed light on the multiple layers of autophagy regulatory mechanisms, and provide novel therapeutic targets for the treatment of the diseases.

Item Type: Book Section
Depositing User: Mr. Rameshwar Nema
Date Deposited: 26 Feb 2020 05:25
Last Modified: 26 Feb 2020 05:25
URI: http://nccs.sciencecentral.in/id/eprint/796

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