Das, S and Bano , S and Kapse , P and Kundu , GC (2022) CRISPR based therapeutics: a new paradigm in cancer precision medicine. Molecular Cancer, 21 (85).

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Abstract

Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated protein (Cas) systems are the latest addition to the plethora of gene-editing tools. These systems have been repurposed from their natural counterparts by means of both guide RNA and Cas nuclease engineering. These RNA-guided systems offer greater programmability and multiplexing capacity than previous generation gene editing tools based on zinc finger nucleases and transcription activator like effector nucleases. CRISPR-Cas systems show great promise for individualization of cancer precision medicine.

Item Type:	Article
Additional Information:	1. School of Biotechnology, KIIT Deemed To Be University, Bhubaneswar, 751024, India 2.National Centre for Cell Science, S P Pune University Campus, Pune, 411007, India (Corresponding Author)
Subjects:	Cancer Biology
Depositing User:	Mr. Rameshwar Nema
Date Deposited:	18 Oct 2022 07:27
Last Modified:	18 Oct 2022 07:27
URI:	http://nccs.sciencecentral.in/id/eprint/1167

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