Nehra , S and Sharma, V and Umrani, M and Singhal, N (2023) Generation of integration-free Down syndrome and isogenic euploid human induced pluripotent stem cells. Stem Cell Research, 67. p. 103041.
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Abstract
A pair of Down syndrome (DS) human iPSCs (hiPSCs) and isogenic euploid hiPSCs generated by using an integration-free Sendai viral vector system showed trisomy 21 (47; XY) and typical (46; XY) karyotype respectively. Pluripotency of both hiPSC lines was confirmed by pluripotency marker expression and three germ layer differentiation potentials.
Item Type: | Article |
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Additional Information: | National Centre for Cell Science (NCCS), Pune 411007, India |
Subjects: | Stem Cell Biology |
Depositing User: | Mr. Rameshwar Nema |
Date Deposited: | 09 Feb 2023 06:45 |
Last Modified: | 09 Feb 2023 06:45 |
URI: | http://nccs.sciencecentral.in/id/eprint/1246 |
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