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Nehra , S and Sharma, V and Umrani, M and Singhal, N (2023) Generation of integration-free Down syndrome and isogenic euploid human induced pluripotent stem cells. Stem Cell Research, 67. p. 103041.

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Abstract

A pair of Down syndrome (DS) human iPSCs (hiPSCs) and isogenic euploid hiPSCs generated by using an integration-free Sendai viral vector system showed trisomy 21 (47; XY) and typical (46; XY) karyotype respectively. Pluripotency of both hiPSC lines was confirmed by pluripotency marker expression and three germ layer differentiation potentials.

Item Type: Article
Additional Information: National Centre for Cell Science (NCCS), Pune 411007, India
Subjects: Stem Cell Biology
Depositing User: Mr. Rameshwar Nema
Date Deposited: 09 Feb 2023 06:45
Last Modified: 09 Feb 2023 06:45
URI: http://nccs.sciencecentral.in/id/eprint/1246

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