Nehra , S and Sharma, V and Umrani, M and Singhal, N (2023) Generation of integration-free Down syndrome and isogenic euploid human induced pluripotent stem cells. Stem Cell Research, 67. p. 103041.
Full text not available from this repository. (Request a copy)
      Official URL: https://www.sciencedirect.com/science/article/pii/...
    
  
  
    Abstract
A pair of Down syndrome (DS) human iPSCs (hiPSCs) and isogenic euploid hiPSCs generated by using an integration-free Sendai viral vector system showed trisomy 21 (47; XY) and typical (46; XY) karyotype respectively. Pluripotency of both hiPSC lines was confirmed by pluripotency marker expression and three germ layer differentiation potentials.
| Item Type: | Article | 
|---|---|
| Additional Information: | National Centre for Cell Science (NCCS), Pune 411007, India | 
| Subjects: | Stem Cell Biology | 
| Depositing User: | Mr. Rameshwar Nema | 
| Date Deposited: | 09 Feb 2023 06:45 | 
| Last Modified: | 09 Feb 2023 06:45 | 
| URI: | http://nccs.sciencecentral.in/id/eprint/1246 | 
Actions (login required)
![]()  | 
        View Item | 
        
        