Spehlmanna, ME and Dhotre, DP and Schmiedel, N and Chavan, N and Bang , C and Rangrez, AY (2022) Dataset of ileum bacterial diversity in mice after heart failure due to pressure overload. Data in Brief. p. 108498.

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Abstract

We recently reported the correlation of gut bacterial diversity with heart failure using a mouse model of heart failure due to pressure overload induced by transverse aortic constriction (TAC). We found that gut the bacterial diversity is significantly altered and is directly correlated to the severity of heart failure (Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations (Spehlmann, 2022). In addition, stool samples that were collected for the gut microbial diversity analysis, we dissected ileum from the mice after 42 days of TAC. The total DNA was extracted to identify the bacterial diversity resided in ileum using 16S rRNA gene amplicon shotgun sequencing and downstream bioinformatics analysis to determine if it is correlated to the heart

Item Type:	Article
Subjects:	Insect Molecular Biology
Depositing User:	Mr. Rameshwar Nema
Date Deposited:	20 Oct 2022 06:52
Last Modified:	20 Oct 2022 06:52
URI:	http://nccs.sciencecentral.in/id/eprint/1188

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