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Hussain , A and Hassan , QP and Shouche, YS (2020) New approaches for antituberculosis leads from Actinobacteria. Drug Discovery Today, 25 (12). pp. 2335-2342.

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Abstract

Bioactive metabolites derived from the phylum Actinobacteria represent many of the existing antimicrobial drugs. Compared with other bacterial pathogens, direct preliminary screening by diffusion assays is a limiting factor against Mycobacterium tuberculosis (Mtb) and different methodologies have been used to improve the search for new molecules. However, the concern remains that most of the previously discovered molecules replicate by conventional procedures. The combination of multidisciplinary approaches with new technologies could advance the discovery of new leads against Mtb like considering the unexplored Actinobacteria jointly with selective and integrative procedures.

Item Type: Article
Subjects: Insect Molecular Biology
Depositing User: Mr. Rameshwar Nema
Date Deposited: 17 Nov 2021 07:31
Last Modified: 17 Nov 2021 07:31
URI: http://nccs.sciencecentral.in/id/eprint/993

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